- Home
- ยป
- Our Products
- »
- Anti Viral Medicines
Anti Viral Medicines
Myhep Sofosbuvir 400 Mg Tablets
Product Brochure
Dose/Strength | 400 mg |
Packaging Type | Bottle |
Composition | Sofosbuvir 400mg |
Manufactured By | Mylan Pharmaceuticals Private Limited |
Form | Tablet |
Also gives | Third Party Manufacturing |
Country of Origin | Made in India |
Myhep Tablet should be taken in the dose and duration as advised by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. It should be taken with food, preferably at a fixed time. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
It has fewer side effects as compared to other similar medicines, like fatigue, headache, nausea, insomnia (difficulty sleeping) and anemia (low red blood cell count). Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding.
Sofovir Tablets 400 Mg
Product Brochure
Dose/Strength | 400 mg |
Packaging Size | 1X7 |
Composition | Sofosbuvir Tablets |
Packaging Type | Bottle |
Manufactured By | Hetero pharma |
Form | Tablet |
Also gives | Third Party Manufacturing |
Country of Origin | Made in India |
- Composition: Sofosbuvir Tablets
- Brand Name: Sofovir
- Strength: 400mg
- Packing: 7 Tablet
Product Description
Sofosbuvir tablets are administered orally. Each tablet contains 400 mg of sofosbuvir.
- Taken with or without food
- Low indication of side effects
- Effective anti viral drug
INDICATIONS AND USAGE
Sofosbuvir is indicated in combination with other medical products for the treatment of chronic hepatitis C (CHC) in adults.
DOSAGES AND ADMINISTRATION
Recommended Dose in adults
The recommended dose of sofosbuvir is one 400 mg tablet, taken orally, once daily with or without food sofosbuvir should be used combination with ribavirin or in combination with pegylated interferon and ribavirin for the treatment of CHC in adults.The recommended regimen and treatment duration for the sofosbuvir combination therapy is provided in following table.Dose Modification:
Genotype 1 and 4:
If a patients has a serious adverse reaction potentially related to peginterferon alfa and /or ribavirin, the peginterferon alfa and/or ribavirin dose should be reduced or discontinued. Refer to the peginterferon alfa and ribavirin prescribing information for the additional information about how to reduce and/or discontinue the peginterferon alfa and/or ribavirin dose.
Genotype 2 and 3:
If a patient has a serious adverse reaction potentially related to ribavirin, the ribavirin dose should be modified or discontinued, if appropriate, until the adverse reaction abates or decreases in sverity.Provides guidelines for dose modifications and discontinuation based on the patient’s hemoglobin concentration and cardiac status.
DOSAGES FORMS AND STRENGTHS
Each film coated tablet of sofosbuvir 400 mg is available as capsules shaped, brick red colored and debossed with 400 on one side and plain on another side.
CONTRAINDICATIONS
sofovir is used in combination with ribavirin to peginterferon alfa/ribavirin; the contraindications applicable to those agents are applicable to combination therapies. Refer to the prescribing information of peginterferon alfa and ribavirin for a list of their contraindications.
WARNINGS AND PRECAUTIONS
Pregnancy:
Use with Ribavirin or Peginterferon Alfa/Ribavirin
Ribavirin may cause birth defects and /or deaths of the exposed fetus and animal have shown that interferons have abortifacient effects. Extreme care must be taken to avoid pregnancy in female patients and in female partners of male patients. Ribavirin therapy should not be started unless a report of a negative pregnancy test has been obtained immediately prior to initiation of therapy.
When sofovir is used in combinations with ribavirin or peginterferon alfa/ribavirin, women of childbearing potential and their male partners must use two forms of effective contraception during treatment and for at least 6 months after treatment. Monthly pregnancy tests must be performed during this time. There are no data on the effectiveness of systemic hormonal contraceptives in women taking sofovir therefore, two non-hormonal methods of contraception should be used during treatment with sofovir and concomitant ribavirin.
ADVERSE REACTIONS
The most common adverse events (>=20%) for sofosbuvir + ribavirin combination therapy were fatigue and headache. The most common adverse events (>=20%) for sofosbuvir+ peginterferon alfa+ ribavirin combination therapy were fatigue, headache, nausea, in-somnia and anemia.